The fundamental concepts of protein architecture and dynamics are presented with an emphasis on the functional outcomes of chemistry coordinated in three dimensional space. Catalytic mechanics and enzyme function are outlined in detail. Current methods in the determination of enzyme structure and function will be discussed, and students will use common tools in macromolecular analysis and structural modeling. Case studies in enzyme dysfunction, disease, and current research will be used throughout the course.
The following three courses, CH 4110, CH 4120, and CH 4130, are a three-term sequence intended to provide a strong emphasis in biochemistry.
Recommended Background