This laboratory course focuses on the application of modern instrumental methods of analysis to chemical, biochemical and environmental problems. Practical experience is gained in quantitative electrochemistry, ultraviolet-visible spectrophotometry, fluorometry and bioluminescence, high performance liquid chromatography, and capillary electrophoresis. Principles of experimental design and execution are developed as student teams select a chemical, biochemical or environmental problem, formulate an approach, conduct the analysis, and present findings to the class. Methods of data analysis and common statistical approaches are emphasized throughout the course.